טוען...

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Vaso-occlusive crisis (VOC) is the primary cause of morbidity and hospitalization in sickle cell disease (SCD); however, only 4 therapies (hydroxyurea, l-glutamine, crizanlizumab, and voxeletor) are currently approved in SCD. These agents limit the duration, severity, and frequency of crises. Activa...

תיאור מלא

שמור ב:

מידע ביבליוגרפי
הוצא לאור ב:	Blood
Main Authors:	Sparkenbaugh, Erica M., Chen, Chunsheng, Brzoska, Tomasz, Nguyen, Julia, Wang, Shaobin, Vercellotti, Gregory M., Key, Nigel S., Sundd, Prithu, Belcher, John D., Pawlinski, Rafal
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society of Hematology 2020
נושאים:	Red Cells, Iron, and Erythropoiesis
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7225686/ https://ncbi.nlm.nih.gov/pubmed/31977004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003543
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

פריטים דומים