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P-selectin deficiency promotes liver senescence in sickle cell disease mice
Sickle cell disease (SCD) is caused by a homozygous mutation in the β-globin gene, which leads to erythrocyte sickling, vasoocclusion, and intense hemolysis. P-selectin inhibition has been shown to prevent vasoocclusive events in patients with SCD; however, the chronic effect of P-selectin inhibitio...
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| Yayımlandı: | Blood |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8120139/ https://ncbi.nlm.nih.gov/pubmed/33619560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020009779 |
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