SPOP promotes ubiquitination and degradation of MyD88 to suppress the innate immune response

As a canonical adaptor for the Toll-like receptor (TLR) family, myeloid differentiation primary response protein 88 (MyD88) has crucial roles in host defense against infection by microbial pathogens, and its dysregulation might induce autoimmune diseases. Here, we demonstrate that the chicken Cullin...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Li, Qinghe, Wang, Fei, Wang, Qiao, Zhang, Na, Zheng, Jumei, Zheng, Maiqing, Liu, Ranran, Cui, Huanxian, Wen, Jie, Zhao, Guiping
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224567/
https://ncbi.nlm.nih.gov/pubmed/32365080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008188
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