The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation

The response to systemic infection and injury requires the rapid adaptation of hematopoietic stem cells (HSCs), which proliferate and divert their differentiation toward the myeloid lineage. Significant interest has emerged in understanding the signals that trigger the emergency hematopoietic progra...

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Publicado no:Nat Immunol
Main Authors: Guillamot, Maria, Ouazia, Dahmane, Dolgalev, Igor, Yeung, Stephen T., Kourtis, Nikos, Dai, Yuling, Corrigan, Kate, Zea-Redondo, Luna, Saraf, Anita, Florens, Laurence, Washburn, Michael P., Tikhonova, Anastasia N., Malumbres, Marina, Gong, Yixiao, Tsirigos, Aristotelis, Park, Christopher, Barbieri, Christopher, Khanna, Kamal M., Busino, Luca, Aifantis, Iannis
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376385/
https://ncbi.nlm.nih.gov/pubmed/31406379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0454-6
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