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Hsp70 molecular chaperones: multifunctional allosteric holding and unfolding machines

The Hsp70 family of chaperones works with its co-chaperones, the nucleotide exchange factors and J-domain proteins, to facilitate a multitude of cellular functions. Central players in protein homeostasis, these jacks-of-many-trades are utilized in a variety of ways because of their ability to bind w...

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Bibliographic Details
Published in:Biochem J
Main Authors: Clerico, Eugenia M., Meng, Wenli, Pozhidaeva, Alexandra, Bhasne, Karishma, Petridis, Constantine, Gierasch, Lila M.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219557/
https://ncbi.nlm.nih.gov/pubmed/31201219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170380
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