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Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

The 70-kDa heat shock protein (Hsp70) chaperones perform a wide array of cellular functions that all derive from the ability of their N-terminal nucleotide-binding domains (NBDs) to allosterically regulate the substrate affinity of their C-terminal substrate-binding domains in a nucleotide-dependent...

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Detalhes bibliográficos
Main Authors: Zhuravleva, Anastasia, Gierasch, Lila M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084084/
https://ncbi.nlm.nih.gov/pubmed/21482798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014448108
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