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Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2

The human zinc transporter SLC39A2, also known as ZIP2, was shown to mediate zinc transport that could be inhibited at pH <7.0 and stimulated by HCO(3)(−), suggesting a Zn(2+)/HCO(3)(−) cotransport mechanism [Gaither, L. A., and Eide, D. J. (2000) J. Biol. Chem. 275, 5560–5564]. In contrast, rece...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Franz, Marie C., Pujol-Giménez, Jonai, Montalbetti, Nicolas, Fernandez-Tenorio, Miguel, DeGrado, Timothy R., Niggli, Ernst, Romero, Michael F., Hediger, Matthias A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218795/
https://ncbi.nlm.nih.gov/pubmed/29791142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00511
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