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Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2

The human zinc transporter SLC39A2, also known as ZIP2, was shown to mediate zinc transport that could be inhibited at pH <7.0 and stimulated by HCO(3)(−), suggesting a Zn(2+)/HCO(3)(−) cotransport mechanism [Gaither, L. A., and Eide, D. J. (2000) J. Biol. Chem. 275, 5560–5564]. In contrast, rece...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Franz, Marie C., Pujol-Giménez, Jonai, Montalbetti, Nicolas, Fernandez-Tenorio, Miguel, DeGrado, Timothy R., Niggli, Ernst, Romero, Michael F., Hediger, Matthias A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218795/
https://ncbi.nlm.nih.gov/pubmed/29791142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00511
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