Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2

The human zinc transporter SLC39A2, also known as ZIP2, was shown to mediate zinc transport that could be inhibited at pH <7.0 and stimulated by HCO(3)(−), suggesting a Zn(2+)/HCO(3)(−) cotransport mechanism [Gaither, L. A., and Eide, D. J. (2000) J. Biol. Chem. 275, 5560–5564]. In contrast, rece...

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Publicado en:Biochemistry
Main Authors: Franz, Marie C., Pujol-Giménez, Jonai, Montalbetti, Nicolas, Fernandez-Tenorio, Miguel, DeGrado, Timothy R., Niggli, Ernst, Romero, Michael F., Hediger, Matthias A.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218795/
https://ncbi.nlm.nih.gov/pubmed/29791142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00511
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