Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2

The human zinc transporter SLC39A2, also known as ZIP2, was shown to mediate zinc transport that could be inhibited at pH <7.0 and stimulated by HCO(3)(−), suggesting a Zn(2+)/HCO(3)(−) cotransport mechanism [Gaither, L. A., and Eide, D. J. (2000) J. Biol. Chem. 275, 5560–5564]. In contrast, rece...

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Vydáno v:Biochemistry
Hlavní autoři: Franz, Marie C., Pujol-Giménez, Jonai, Montalbetti, Nicolas, Fernandez-Tenorio, Miguel, DeGrado, Timothy R., Niggli, Ernst, Romero, Michael F., Hediger, Matthias A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218795/
https://ncbi.nlm.nih.gov/pubmed/29791142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00511
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