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Discovery of endogenous inverse agonists for G protein-coupled receptor 6

The orphan G protein-coupled receptor 6 (GPR6) is highly expressed in the striatum and1 has been linked to multiple striatal pathologies. The identification of endogenous ligands and their mechanisms of action at GPR6 will help to elucidate the physiological and pathological roles of the receptor. I...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Shrader, Sarah H., Song, Zhao-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7218748/
https://ncbi.nlm.nih.gov/pubmed/31818461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.12.004
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