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5-HT(1B) RECEPTOR-MEDIATED ACTIVATION OF ERK1/2 REQUIRES BOTH Gα(i/o) AND β-ARRESTIN PROTEINS
5-HT(1B) receptors modulate synaptic serotonin (5-HT) levels and play a significant role in the regulation of emotional behaviors. These receptors are Gα(i/o)-coupled and inhibit adenylyl cyclase but have also been reported to activate MAP kinases; however, the details of signaling cascades downstre...
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| Pubblicato in: | ACS Chem Neurosci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7217031/ https://ncbi.nlm.nih.gov/pubmed/30946562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00596 |
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