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Restoration of Physiological Expression of 5-HT(6) Receptor into the Primary Cilia of Null Mutant Neurons Lengthens Both Primary Cilia and Dendrites

5-HT(6) (serotonin) receptors are promising targets for a variety of neuropsychiatric disorders and have been linked to several cellular signaling cascades. Endogenous 5-HT(6) receptors are restricted to the primary neuronal cilium, a small sensory organelle stemming from the cell body that receives...

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Опубликовано в: :Mol Pharmacol
Главные авторы: Lesiak, Atom J., Brodsky, Matthew, Cohenca, Nathalie, Croicu, Alexandra G., Neumaier, John F.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987994/
https://ncbi.nlm.nih.gov/pubmed/29678909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.111583
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