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Cannabinoid Agonists Increase the Interaction between β-Arrestin 2 and ERK1/2 and Upregulate β-Arrestin 2 and 5-HT(2A) Receptors

We have recently reported that selective cannabinoid 2 (CB(2)) receptor agonists upregulate 5-HT(2A) receptors by enhancing ERK1/2 signaling in prefrontal cortex (PFCx). Increased activity of cortical 5-HT(2A) receptors has been associated with several neuropsychiatric disorders such as anxiety and...

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Detalhes bibliográficos
Main Authors: Franklin, Jade M., Vasiljevik, Tamara, Prisinzano, Thomas E., Carrasco, Gonzalo A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562593/
https://ncbi.nlm.nih.gov/pubmed/23174265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2012.11.002
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