Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

The cyclin-dependent kinase 1 (Cdk1) drives cell division. To uncover additional functions of Cdk1, we generated knock-in mice expressing an analog-sensitive version of Cdk1 in place of wild-type Cdk1. In our study we focused on embryonic stem (ES) cells, as this cell type displays particularly high...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Michowski, Wojciech, Chick, Joel M., Chu, Chen, Kolodziejczyk, Aleksandra, Wang, Yichen, Suski, Jan M., Abraham, Brian, Anders, Lars, Day, Daniel, Dunkl, Lukas M., Man, Mitchell Li Cheong, Zhang, Tian, Laphanuwat, Phatthamon, Bacon, Nickolas A., Liu, Lijun, Fassl, Anne, Sharma, Samanta, Otto, Tobias, Jecrois, Emanuelle, Han, Richard, Sweeney, Katharine E., Marro, Samuele, Wernig, Marius, Geng, Yan, Moses, Alan, Li, Cheng, Gygi, Steven P., Young, Richard A., Sicinski, Piotr
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214218/
https://ncbi.nlm.nih.gov/pubmed/32240602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.010
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