Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

The cyclin-dependent kinase 1 (Cdk1) drives cell division. To uncover additional functions of Cdk1, we generated knock-in mice expressing an analog-sensitive version of Cdk1 in place of wild-type Cdk1. In our study we focused on embryonic stem (ES) cells, as this cell type displays particularly high...

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Publicado no:Mol Cell
Main Authors: Michowski, Wojciech, Chick, Joel M., Chu, Chen, Kolodziejczyk, Aleksandra, Wang, Yichen, Suski, Jan M., Abraham, Brian, Anders, Lars, Day, Daniel, Dunkl, Lukas M., Man, Mitchell Li Cheong, Zhang, Tian, Laphanuwat, Phatthamon, Bacon, Nickolas A., Liu, Lijun, Fassl, Anne, Sharma, Samanta, Otto, Tobias, Jecrois, Emanuelle, Han, Richard, Sweeney, Katharine E., Marro, Samuele, Wernig, Marius, Geng, Yan, Moses, Alan, Li, Cheng, Gygi, Steven P., Young, Richard A., Sicinski, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214218/
https://ncbi.nlm.nih.gov/pubmed/32240602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.010
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