Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

The cyclin-dependent kinase 1 (Cdk1) drives cell division. To uncover additional functions of Cdk1, we generated knock-in mice expressing an analog-sensitive version of Cdk1 in place of wild-type Cdk1. In our study we focused on embryonic stem (ES) cells, as this cell type displays particularly high...

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Publicat a:Mol Cell
Autors principals: Michowski, Wojciech, Chick, Joel M., Chu, Chen, Kolodziejczyk, Aleksandra, Wang, Yichen, Suski, Jan M., Abraham, Brian, Anders, Lars, Day, Daniel, Dunkl, Lukas M., Man, Mitchell Li Cheong, Zhang, Tian, Laphanuwat, Phatthamon, Bacon, Nickolas A., Liu, Lijun, Fassl, Anne, Sharma, Samanta, Otto, Tobias, Jecrois, Emanuelle, Han, Richard, Sweeney, Katharine E., Marro, Samuele, Wernig, Marius, Geng, Yan, Moses, Alan, Li, Cheng, Gygi, Steven P., Young, Richard A., Sicinski, Piotr
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214218/
https://ncbi.nlm.nih.gov/pubmed/32240602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.010
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