Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression

Studies on macrophage gene expression have historically focused on events leading to RNA polymerase II recruitment and transcription initiation, whereas the contribution of post-initiation steps to macrophage activation remains poorly understood. Here, we report that widespread promoter-proximal RNA...

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Vydáno v:Nat Commun
Hlavní autoři: Yu, Li, Zhang, Bin, Deochand, Dinesh, Sacta, Maria A., Coppo, Maddalena, Shang, Yingli, Guo, Ziyi, Zeng, Xiaomin, Rollins, David A., Tharmalingam, Bowranigan, Li, Rong, Chinenov, Yurii, Rogatsky, Inez, Hu, Xiaoyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210294/
https://ncbi.nlm.nih.gov/pubmed/32385332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16209-5
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