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The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis
Diet-induced obesity causes chronic macrophage-driven inflammation in white adipose tissue (WAT) leading to insulin resistance. WAT macrophages, however, differ in their origin, gene expression and activities: unlike infiltrating monocyte-derived inflammatory macrophages, WAT-resident macrophages co...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974480/ https://ncbi.nlm.nih.gov/pubmed/27464507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12254 |
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