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Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids

Inhibition of cytokine gene expression by the hormone-activated glucocorticoid receptor (GR) is the key component of the anti-inflammatory actions of glucocorticoids, yet the underlying molecular mechanisms remain obscure. Here we report that glucocorticoid repression of cytokine genes in primary ma...

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Bibliografiske detaljer
Main Authors: Chinenov, Yurii, Gupte, Rebecca, Dobrovolna, Jana, Flammer, Jamie R., Liu, Bill, Michelassi, Francesco E., Rogatsky, Inez
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406827/
https://ncbi.nlm.nih.gov/pubmed/22753499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206059109
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