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Heterochromatin drives compartmentalization of inverted and conventional nuclei
The mammalian cell nucleus displays a distinct spatial segregation of active euchromatic from inactive heterochromatic genomic regions(1,2). In conventional nuclei, microscopy shows that euchromatin is localized in the nuclear interior and heterochromatin at the nuclear periphery(1,2). Hi-C shows th...
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| Gepubliceerd in: | Nature |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206897/ https://ncbi.nlm.nih.gov/pubmed/31168090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1275-3 |
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