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Iterative Correction of Hi-C Data Reveals Hallmarks of Chromosome Organization
Extracting biologically meaningful information from chromosomal interactions obtained with genome-wide chromosome conformation capture (3C) analyses requires elimination of systematic biases. We present a pipeline that integrates a strategy for mapping of sequencing reads and a data-driven method fo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816492/ https://ncbi.nlm.nih.gov/pubmed/22941365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2148 |
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