Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer’s disease

BACKGROUND: Proteomic characterization of microglia provides the most proximate assessment of functionally relevant molecular mechanisms of neuroinflammation. However, microglial proteomics studies have been limited by low cellular yield and contamination by non-microglial proteins using existing en...

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Bibliografski detalji
Izdano u:Mol Neurodegener
Glavni autori: Rayaprolu, Sruti, Gao, Tianwen, Xiao, Hailian, Ramesha, Supriya, Weinstock, Laura D., Shah, Jheel, Duong, Duc M., Dammer, Eric B., Webster, James A., Lah, James J., Wood, Levi B., Betarbet, Ranjita, Levey, Allan I., Seyfried, Nicholas T., Rangaraju, Srikant
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206797/
https://ncbi.nlm.nih.gov/pubmed/32381088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00377-5
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