Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer’s disease

BACKGROUND: Proteomic characterization of microglia provides the most proximate assessment of functionally relevant molecular mechanisms of neuroinflammation. However, microglial proteomics studies have been limited by low cellular yield and contamination by non-microglial proteins using existing en...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Rayaprolu, Sruti, Gao, Tianwen, Xiao, Hailian, Ramesha, Supriya, Weinstock, Laura D., Shah, Jheel, Duong, Duc M., Dammer, Eric B., Webster, James A., Lah, James J., Wood, Levi B., Betarbet, Ranjita, Levey, Allan I., Seyfried, Nicholas T., Rangaraju, Srikant
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206797/
https://ncbi.nlm.nih.gov/pubmed/32381088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00377-5
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