Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis

Hypomagnesemia is a significant risk factor for critically ill patients to develop sepsis, a life-threatening disease with a mortality rate over 25%. Our clinic data analysis showed that hypomagnesemia is associated with a decreased monocyte count in septic patients. At the cellular level, we found...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Wang, Dingyu, Zheng, Jiashuo, Hu, Qiongyuan, Zhao, Cheng, Chen, Qianyue, Shi, Peiliang, Chen, Qin, Zou, Yujie, Zou, Dayuan, Liu, Qiyao, Pei, Jingwen, Wu, Xiuwen, Gao, Xiang, Ren, Jianan, Lin, Zhaoyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206066/
https://ncbi.nlm.nih.gov/pubmed/31209359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0366-x
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