OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer

Methionine-1 (M1)-linked polyubiquitin chains conjugated by the linear ubiquitin chain assembly complex (LUBAC) control NF-κB activation, immune homoeostasis, and prevents tumour necrosis factor (TNF)-induced cell death. The deubiquitinase OTULIN negatively regulates M1-linked polyubiquitin signalli...

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Bibliografiska uppgifter
I publikationen:Cell Death Differ
Huvudupphovsmän: Damgaard, Rune Busk, Jolin, Helen E., Allison, Michael E. D., Davies, Susan E., Titheradge, Hannah L., McKenzie, Andrew N. J., Komander, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206033/
https://ncbi.nlm.nih.gov/pubmed/32231246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0532-1
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