OTULIN restricts Met1-linked ubiquitination to control innate immune signaling

Conjugation of Met1-linked polyubiquitin (Met1-Ub) by the linear ubiquitin chain assembly complex (LUBAC) is an important regulatory modification in innate immune signaling. So far, only few Met1-Ub substrates have been described and the regulatory mechanisms have remained elusive. We recently ident...

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Autors principals: Fiil, Berthe Katrine, Damgaard, Rune Busk, Wagner, Sebastian Alexander, Keusekotten, Kirstin, Fritsch, Melanie, Bekker-Jensen, Simon, Mailand, Niels, Choudhary, Chunaram, Komander, David, Gyrd-Hansen, Mads
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194427/
https://ncbi.nlm.nih.gov/pubmed/23806334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.06.004
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