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OTULIN restricts Met1-linked ubiquitination to control innate immune signaling
Conjugation of Met1-linked polyubiquitin (Met1-Ub) by the linear ubiquitin chain assembly complex (LUBAC) is an important regulatory modification in innate immune signaling. So far, only few Met1-Ub substrates have been described and the regulatory mechanisms have remained elusive. We recently ident...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4194427/ https://ncbi.nlm.nih.gov/pubmed/23806334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.06.004 |
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