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Molecular Basis and Regulation of OTULIN-LUBAC Interaction
The linear ubiquitin (Ub) chain assembly complex (LUBAC) generates Met1-linked “linear” Ub chains that regulate the activation of the nuclear factor κB (NFκB) transcription factor and other processes. We recently discovered OTULIN as a deubiquitinase that specifically cleaves Met1-linked polyUb. Now...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017264/ https://ncbi.nlm.nih.gov/pubmed/24726323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.03.018 |
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