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OTULIN deficiency causes auto-inflammatory syndrome
Ubiquitin chains assembled via the N-terminal methionine (Met1 or linear ubiquitin), conjugated by the linear ubiquitin chain assembly complex (LUBAC), participate in NF-κΒ-dependent inflammatory signaling and immune responses. A recent report in Cell finds that OTULIN, a deubiquitinase that selecti...
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| Publicado en: | Cell Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5099863/ https://ncbi.nlm.nih.gov/pubmed/27686184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.113 |
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