OTULIN deficiency causes auto-inflammatory syndrome

Ubiquitin chains assembled via the N-terminal methionine (Met1 or linear ubiquitin), conjugated by the linear ubiquitin chain assembly complex (LUBAC), participate in NF-κΒ-dependent inflammatory signaling and immune responses. A recent report in Cell finds that OTULIN, a deubiquitinase that selecti...

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Publicat a:Cell Res
Autors principals: Fiil, Berthe Katrine, Gyrd-Hansen, Mads
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Research Highlight
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099863/
https://ncbi.nlm.nih.gov/pubmed/27686184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.113
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