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USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity

USP22, the deubiquitinating subunit of the SAGA transcriptional cofactor complex, is a member of an 11-gene “death-from-cancer” signature. USP22 has been considered an attractive therapeutic target since high levels of its expression were associated with distant metastasis, poor survival, and high r...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Differ
Egile Nagusiak: Kosinsky, Robyn Laura, Zerche, Maria, Saul, Dominik, Wang, Xin, Wohn, Luisa, Wegwitz, Florian, Begus-Nahrmann, Yvonne, Johnsen, Steven A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205880/
https://ncbi.nlm.nih.gov/pubmed/31527800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0420-8
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