USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response

The Ubiquitin-Specific Protease 22 (USP22) is a deubiquitinating subunit of the mammalian SAGA transcriptional co-activating complex. USP22 was identified as a member of the so-called “death-from-cancer” signature predicting therapy failure in cancer patients. However, the importance and functional...

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Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Prokakis, Evangelos, Dyas, Anna, Grün, Regina, Fritzsche, Sonja, Bedi, Upasana, Kazerouni, Zahra B., Kosinsky, Robyn L., Johnsen, Steven A., Wegwitz, Florian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195738/
https://ncbi.nlm.nih.gov/pubmed/34007022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01814-5
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