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USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity
USP22, the deubiquitinating subunit of the SAGA transcriptional cofactor complex, is a member of an 11-gene “death-from-cancer” signature. USP22 has been considered an attractive therapeutic target since high levels of its expression were associated with distant metastasis, poor survival, and high r...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205880/ https://ncbi.nlm.nih.gov/pubmed/31527800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0420-8 |
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