Loss of RNF40 Decreases NF-κB Activity in Colorectal Cancer Cells and Reduces Colitis Burden in Mice

BACKGROUND AND AIMS: Inflammatory bowel diseases are linked to an increased risk of developing colorectal cancer [CRC]. Previous studies suggested that the H2B ubiquitin ligase RING finger protein-20 [RNF20] inhibited inflammatory signaling mediated by the nuclear factor kappa-light-chain-enhancer o...

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Detalhes bibliográficos
Publicado no:J Crohns Colitis
Main Authors: Kosinsky, Robyn Laura, Chua, Robert Lorenz, Qui, Martin, Saul, Dominik, Mehlich, Dawid, Ströbel, Philipp, Schildhaus, Hans-Ulrich, Wegwitz, Florian, Faubion, William A, Johnsen, Steven A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599279/
https://ncbi.nlm.nih.gov/pubmed/30321325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjy165
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