The E3 ubiquitin ligase RNF40 suppresses apoptosis in colorectal cancer cells

BACKGROUND: Colorectal cancer (CRC) is the fourth leading cause of cancer-related deaths worldwide, and deciphering underlying molecular mechanism is essential. The loss of monoubiquitinated histone H2B (H2Bub1) was correlated with poor prognosis of CRC patients and, accordingly, H2Bub1 was suggeste...

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Publicado en:Clin Epigenetics
Main Authors: Schneider, Deborah, Chua, Robert Lorenz, Molitor, Nicole, Hamdan, Feda H., Rettenmeier, Eva Maria, Prokakis, Evangelos, Mishra, Vivek Kumar, Kari, Vijayalakshmi, Wegwitz, Florian, Johnsen, Steven A., Kosinsky, Robyn Laura
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604314/
https://ncbi.nlm.nih.gov/pubmed/31266541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0698-x
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