USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer

As a member of the 11-gene “death-from-cancer” gene expression signature, overexpression of the Ubiquitin-Specific Protease 22 (USP22) was associated with poor prognosis in various human malignancies. To investigate the function of USP22 in cancer development and progression, we sought to detect com...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Kosinsky, Robyn Laura, Helms, Marlena, Zerche, Maria, Wohn, Luisa, Dyas, Anna, Prokakis, Evangelos, Kazerouni, Zahra Basir, Bedi, Upasana, Wegwitz, Florian, Johnsen, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892875/
https://ncbi.nlm.nih.gov/pubmed/31801945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2141-9
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