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BH3 profiling discriminates on-target small molecule BH3 mimetics from putative mimetics
Inhibition of the anti-apoptotic machinery of cancer cells is a promising therapeutic approach that has driven the development of an important class of compounds termed “BH3 mimetics”. These novel small molecules mimic BH3-only proteins by antagonizing the pro-survival function of anti-apoptotic pro...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Death Differ |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205860/ https://ncbi.nlm.nih.gov/pubmed/31332296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0391-9 |
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