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Dynamic BH3 profiling identifies active BH3 mimetic combinations in non-small cell lung cancer

Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it remains a top priority. Drug-induced mitochondrial apoptotic priming, measured by dynamic BH3 profiling (DBP), has been shown in multiple cancers to identify drugs that promote apoptosis...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Potter, Danielle S., Du, Ruochen, Bhola, Patrick, Bueno, Raphael, Letai, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316436/
https://ncbi.nlm.nih.gov/pubmed/34315868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04029-4
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