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Dynamic BH3 profiling identifies active BH3 mimetic combinations in non-small cell lung cancer

Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it remains a top priority. Drug-induced mitochondrial apoptotic priming, measured by dynamic BH3 profiling (DBP), has been shown in multiple cancers to identify drugs that promote apoptosis...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Potter, Danielle S., Du, Ruochen, Bhola, Patrick, Bueno, Raphael, Letai, Anthony
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316436/
https://ncbi.nlm.nih.gov/pubmed/34315868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04029-4
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