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BH3-mimetic small molecule inhibits the growth and recurrence of adenoid cystic carcinoma
OBJECTIVES: To evaluate the anti-tumor effect of BM-1197, a new potent and highly specific small molecule inhibitor of Bcl-2/Bcl-x(L), in preclinical models of human adenoid cystic carcinoma (ACC). METHODS: Low passage primary human adenoid cystic carcinoma cells (UM-HACC-2A,-2B,-5,-6) and patient-d...
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| Pubblicato in: | Oral Oncol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532618/ https://ncbi.nlm.nih.gov/pubmed/26121939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2015.06.004 |
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