Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma

PURPOSE: There are no effective treatment options for patients with advanced adenoid cystic carcinoma (ACC). Here, we evaluated the effect of a new small molecule inhibitor of the MDM2-p53 interaction (MI-773) in preclinical models of ACC. EXPERIMENTAL DESIGN: To evaluate the anti-tumor effect of MI...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Warner, Kristy A., Nör, Felipe, Acasigua, Gerson A., Martins, Manoela D., Zhang, Zhaocheng, McLean, Scott A., Spector, Matthew E., Chepeha, Douglas B., Helman, Joseph, Wick, Michael J., Moskaluk, Christopher A., Castilho, Rogerio M., Pearson, Alexander T., Wang, Shaomeng, Nör, Jacques E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947417/
https://ncbi.nlm.nih.gov/pubmed/26936915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1698
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