Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma

PURPOSE: There are no effective treatment options for patients with advanced adenoid cystic carcinoma (ACC). Here, we evaluated the effect of a new small molecule inhibitor of the MDM2-p53 interaction (MI-773) in preclinical models of ACC. EXPERIMENTAL DESIGN: To evaluate the anti-tumor effect of MI...

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書誌詳細
出版年:Clin Cancer Res
主要な著者: Warner, Kristy A., Nör, Felipe, Acasigua, Gerson A., Martins, Manoela D., Zhang, Zhaocheng, McLean, Scott A., Spector, Matthew E., Chepeha, Douglas B., Helman, Joseph, Wick, Michael J., Moskaluk, Christopher A., Castilho, Rogerio M., Pearson, Alexander T., Wang, Shaomeng, Nör, Jacques E.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947417/
https://ncbi.nlm.nih.gov/pubmed/26936915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1698
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