Llwytho...

Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C‐Src and inhibiting NF‐κB, MAPK and AKT pathways

Angelica sinensis (AS; Dang Gui), a traditional Chinese herb, has for centuries been used for the treatment of bone diseases, including osteoporosis and osteonecrosis. However, the effective ingredient and underlying mechanisms remain elusive. Here, we identified guaiacol as the active component of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Mol Med
Prif Awduron: Zhi, Xin, Fang, Chao, Gu, Yanqiu, Chen, Huiwen, Chen, Xiaofei, Cui, Jin, Hu, Yan, Weng, Weizong, Zhou, Qirong, Wang, Yajun, Wang, Yao, Jiang, Hao, Li, Xiaoqun, Cao, Liehu, Chen, Xiao, Su, Jiacan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205840/
https://ncbi.nlm.nih.gov/pubmed/32185887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15153
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