l‐tetrahydropalmatine suppresses osteoclastogenesis in vivo and in vitro via blocking RANK‐TRAF6 interactions and inhibiting NF‐κB and MAPK pathways

Bone homeostasis is delicately orchestrated by osteoblasts and osteoclasts. Various pathological bone loss situations result from the overactivated osteoclastogenesis. Receptor activator of nuclear factor κB ligand (RANKL)‐activated NF‐κB and MAPK pathways is vital for osteoclastogenesis. Here, we f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Mol Med
Prif Awduron: Zhi, Xin, Wang, Lipeng, Chen, Huiwen, Fang, Chao, Cui, Jin, Hu, Yan, Cao, Liehu, Weng, Weizong, Zhou, Qirong, Qin, Longjuan, Song, Hongyuan, Wang, Yajun, Wang, Yao, Jiang, Hao, Li, Xiaoqun, Wang, Sicheng, Chen, Xiao, Su, Jiacan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933417/
https://ncbi.nlm.nih.gov/pubmed/31725199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14790
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