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l‐tetrahydropalmatine suppresses osteoclastogenesis in vivo and in vitro via blocking RANK‐TRAF6 interactions and inhibiting NF‐κB and MAPK pathways

Bone homeostasis is delicately orchestrated by osteoblasts and osteoclasts. Various pathological bone loss situations result from the overactivated osteoclastogenesis. Receptor activator of nuclear factor κB ligand (RANKL)‐activated NF‐κB and MAPK pathways is vital for osteoclastogenesis. Here, we f...

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書目詳細資料
發表在:J Cell Mol Med
Main Authors: Zhi, Xin, Wang, Lipeng, Chen, Huiwen, Fang, Chao, Cui, Jin, Hu, Yan, Cao, Liehu, Weng, Weizong, Zhou, Qirong, Qin, Longjuan, Song, Hongyuan, Wang, Yajun, Wang, Yao, Jiang, Hao, Li, Xiaoqun, Wang, Sicheng, Chen, Xiao, Su, Jiacan
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933417/
https://ncbi.nlm.nih.gov/pubmed/31725199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14790
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