l‐tetrahydropalmatine suppresses osteoclastogenesis in vivo and in vitro via blocking RANK‐TRAF6 interactions and inhibiting NF‐κB and MAPK pathways

Bone homeostasis is delicately orchestrated by osteoblasts and osteoclasts. Various pathological bone loss situations result from the overactivated osteoclastogenesis. Receptor activator of nuclear factor κB ligand (RANKL)‐activated NF‐κB and MAPK pathways is vital for osteoclastogenesis. Here, we f...

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Publicado no:J Cell Mol Med
Main Authors: Zhi, Xin, Wang, Lipeng, Chen, Huiwen, Fang, Chao, Cui, Jin, Hu, Yan, Cao, Liehu, Weng, Weizong, Zhou, Qirong, Qin, Longjuan, Song, Hongyuan, Wang, Yajun, Wang, Yao, Jiang, Hao, Li, Xiaoqun, Wang, Sicheng, Chen, Xiao, Su, Jiacan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933417/
https://ncbi.nlm.nih.gov/pubmed/31725199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14790
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