Myostatin Promotes Osteoclastogenesis by Regulating Ccdc50 Gene Expression and RANKL-Induced NF-κB and MAPK Pathways

Myostatin is a crucial cytokine that is widely present in skeletal muscle and that negatively regulates the growth and development of muscle cells. Recent research has shown that myostatin might play an essential role in bone metabolism. In RAW264.7 cells and bone marrow monocytes (BMMCs), myostatin...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhi, Xin, Chen, Qian, Song, Shaojun, Gu, Zhengrong, Wei, Wenqiang, Chen, Huiwen, Chen, Xiao, Weng, Weizong, Zhou, Qirong, Cui, Jin, Cao, Liehu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849192/
https://ncbi.nlm.nih.gov/pubmed/33536903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.565163
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