Guaiacol suppresses osteoclastogenesis by blocking interactions of RANK with TRAF6 and C‐Src and inhibiting NF‐κB, MAPK and AKT pathways

Angelica sinensis (AS; Dang Gui), a traditional Chinese herb, has for centuries been used for the treatment of bone diseases, including osteoporosis and osteonecrosis. However, the effective ingredient and underlying mechanisms remain elusive. Here, we identified guaiacol as the active component of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhi, Xin, Fang, Chao, Gu, Yanqiu, Chen, Huiwen, Chen, Xiaofei, Cui, Jin, Hu, Yan, Weng, Weizong, Zhou, Qirong, Wang, Yajun, Wang, Yao, Jiang, Hao, Li, Xiaoqun, Cao, Liehu, Chen, Xiao, Su, Jiacan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205840/
https://ncbi.nlm.nih.gov/pubmed/32185887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15153
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados