Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

Although human endogenous retroviruses (HERVs) represent a substantial proportion of the human genome and some HERVs, such as HERV-K(HML-2), are reported to be involved in neurological disorders, little is known about their biological function. We report that RNA from an HERV-K(HML-2) envelope gene...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Dembny, Paul, Newman, Andrew G., Singh, Manvendra, Hinz, Michael, Szczepek, Michal, Krüger, Christina, Adalbert, Robert, Dzaye, Omar, Trimbuch, Thorsten, Wallach, Thomas, Kleinau, Gunnar, Derkow, Katja, Richard, Bernhard C., Schipke, Carola, Scheidereit, Claus, Stachelscheid, Harald, Golenbock, Douglas, Peters, Oliver, Coleman, Michael, Heppner, Frank L., Scheerer, Patrick, Tarabykin, Victor, Ruprecht, Klemens, Izsvák, Zsuzsanna, Mayer, Jens, Lehnardt, Seija
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205273/
https://ncbi.nlm.nih.gov/pubmed/32271161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131093
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires