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The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration
BACKGROUND: Toll-like receptors (TLRs) enable innate immune cells to respond to pathogen- and host-derived molecules. The central nervous system (CNS) exhibits most of the TLRs identified with predominant expression in microglia, the major immune cells of the brain. Although individual TLRs have bee...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4182775/ https://ncbi.nlm.nih.gov/pubmed/25239168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0166-7 |
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