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The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration

BACKGROUND: Toll-like receptors (TLRs) enable innate immune cells to respond to pathogen- and host-derived molecules. The central nervous system (CNS) exhibits most of the TLRs identified with predominant expression in microglia, the major immune cells of the brain. Although individual TLRs have bee...

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Detalhes bibliográficos
Main Authors: Rosenberger, Karen, Derkow, Katja, Dembny, Paul, Krüger, Christina, Schott, Eckart, Lehnardt, Seija
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182775/
https://ncbi.nlm.nih.gov/pubmed/25239168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0166-7
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