Transcription factor binding at immunoglobulin enhancers is linked to somatic hypermutation targeting

Secondary diversification of the immunoglobulin (Ig) repertoire occurs through somatic hypermutation (SHM), gene conversion (GCV), and class switch recombination (CSR)—three processes that are initiated by activation-induced cytidine deaminase (AID). AID targets Ig genes at rates orders of magnitude...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Eur J Immunol
Main Authors: Dinesh, Ravi K., Barnhill, Benjamin, Ilanges, Anoj, Wu, Lizhen, Michelson, Daniel A., Senigl, Filip, Alinikula, Jukka, Shabanowitz, Jeffrey, Hunt, Donald F., Schatz, David G.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202714/
https://ncbi.nlm.nih.gov/pubmed/31821534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948357
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker