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Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells
The activation induced cytosine deaminase (AID) mediates diversification of B cell immunoglobulin genes by the three distinct yet related processes of somatic hypermutation (SHM), class switch recombination (CSR), and gene conversion (GCV). SHM occurs in germinal center B cells, and the transcriptio...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762950/ https://ncbi.nlm.nih.gov/pubmed/26900682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149146 |
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