Transcription factor binding at immunoglobulin enhancers is linked to somatic hypermutation targeting

Secondary diversification of the immunoglobulin (Ig) repertoire occurs through somatic hypermutation (SHM), gene conversion (GCV), and class switch recombination (CSR)—three processes that are initiated by activation-induced cytidine deaminase (AID). AID targets Ig genes at rates orders of magnitude...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Eur J Immunol
मुख्य लेखकों: Dinesh, Ravi K., Barnhill, Benjamin, Ilanges, Anoj, Wu, Lizhen, Michelson, Daniel A., Senigl, Filip, Alinikula, Jukka, Shabanowitz, Jeffrey, Hunt, Donald F., Schatz, David G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202714/
https://ncbi.nlm.nih.gov/pubmed/31821534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948357
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